![]() A review of recent Severe acute respiratory syndrome-related coronavirus (SARS-CoV) and SARS-CoV-2 medical reports, as well as described characteristics of HP, lead us to postulate a theory for SARS-CoV-2 severe disease. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus responsible for our recent coronavirus disease 2019 pandemic, is driving a lung immunopathology that strongly resembles a severe form of hypersensitivity pneumonitis (HP). Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ĥIntensive & Critical Care Unit, Larkin Health System, South Miami, FL, USA.ĦZymo Research Corporation, Irvine, California, USA. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ĤDepartment of Internal Medicine, Roy J. Rizvi, 1ġDivision of Clinical & Translational Research, Larkin Health System, South Miami, Florida, USA.ģInflammation Program, Roy J. Issuree, 3, 4 George Yatzkan, 5 Syed A. Sanchez-Gonzalez, 1 Dave Moskowitz, 2 Priya D. English.Ĭopyright © 2020 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDSĪ Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation
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